PCOS often stems from hormonal imbalances, particularly elevated levels of androgens (male hormones), disrupting the normal ovulation process and leading to irregular menstrual cycles and follicle development.
Insulin resistance, common in PCOS, causes cells to become less responsive to insulin, leading to increased insulin levels in the bloodstream. This can stimulate androgen production, disrupt ovarian function, and contribute to weight gain.
Genetic factors play a role in PCOS susceptibility, with family history often indicating a higher risk. Specific genetic variations can affect hormone regulation, insulin sensitivity, and ovarian function, contributing to the development of PCOS.
Exposure to certain environmental factors like endocrine-disrupting chemicals (EDCs), found in plastics, pesticides, and personal care products, may influence hormone levels and contribute to the development or exacerbation of PCOS symptoms.
Sedentary lifestyle, poor diet, and obesity are associated with an increased risk of PCOS. Excess weight can worsen insulin resistance, hormonal imbalances, and inflammation, exacerbating PCOS symptoms and complications.
Chronic stress can disrupt the hypothalamic-pituitary-adrenal (HPA) axis and contribute to hormonal imbalances, exacerbating PCOS symptoms such as irregular periods, acne, and weight gain.
Inflammation is implicated in the pathogenesis of PCOS, with elevated levels of inflammatory markers often observed in women with the condition. Chronic low-grade inflammation can contribute to insulin resistance, ovarian dysfunction, and other PCOS-related complications.
Thanks for Reading